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However, given the prolonged half-life of phenobarbital, using massive doses is inadvisable

doi: 10.1056/NEJMoa0810440 495 TingW-HChienM-NLoF-SWangC-HHuangC-YLinC-Let al

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In animal models, the elevated TMAO levels were significantly related to tubulointerstitial fibrosis and collagen deposition in the kidney and TMAO was demonstrated to increase in kidney injury molecule-1, phosphorylation of Smad3 (Tang et al., 2015b)

Identidadee Informaes de Contacto do Responsvel pelo Tratamento Esta poltica de privacidade aplica-se a todos os dados pessoais tratados pela Sensilab d.o.o., com sede social em Verov'kova 55a, 1000 Ljubljana, Eslovnia, nmero de registo da empresa 2113732000, e pela Vision Healthcare Group, com sede social em Grote Markt 41, 8500 Kortrijk, Blgica, nmero de registo da empresa BE 0685.849.188, que atuam como responsveis conjuntos pelo tratamento de dados ao abrigo do RGPD (doravante designadas por "Responsveis pelo Tratamento de Dados")