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This article demonstrates that tirzepatide treatment markedly improves symptoms of obstructive sleep apnoea in people with obesity and obstructive sleep apnoea

that is, low p53 levels lead to growth arrest, while increased p53 levels result in apoptosis ( 2.3 p53 and germ cell death in spermatogenesis The apoptosis of germ cells is a normal phenomenon in spermatogenesis and has been widely observed in SSCs, spermatogonia, spermatocytes and spermatids

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Despite the severe impact on individuals and society, there are no approved treatment options

The crosstalk of endoplasmic reticulum (ER) stress pathways with NF-B: complex mechanisms relevant for cancer, inflammation and infection