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Trina Pico Cell Technology

Activated glial cells release proinflammatory cytokines, such as interleukin1 (IL1) and tumor necrosis factoralpha (TNF), which exacerbate neuronal damage and synaptic loss (Heneka et al

In particular, we hereby propose the putative functionally relevant conformational change of the C terminus after the transfer of reducing equivalents from NADPH to the redox sites of the enzyme.