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Structural characterization of Hericium coralloides polysaccharide and its neuroprotective function in Alzheimer's disease

found that Tan IIA (100 M) can reduce MMP-9 activity by inhibiting ERK1/2/AP-1 and Akt/NF-B signaling pathways, thereby inhibiting HASMC migration (Jin et al., 2008)

The identification of alpha-synuclein as the first parkinson disease gene

Therefore, we optimized our search strategy by categorizing the botanical drugs into metabolites such as flavonoids, polyphenols, terpenoids, alkaloids, saponins, and anthraquinones, and combining these with more specific keywords like ALD, alcohol-related liver disease, alcoholic liver disease, oxidative stress, and ROS to improve the search accuracy

It helps remove damaged proteins, neutralizes lipid peroxidation products, and assists in eliminating cellular debris

However, these two studies were retracted, partly due to the negative results of a large scale RCT, namely the TRIPSS study