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Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

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147 Superoxide and hydroxyl radicals drive intrinsic apoptosis by disrupting mitochondrial membrane potential, whereas H 2 O 2 promotes extrinsic apoptosis by inducing c-FLIP ubiquitination and proteasomal degradation, enabling caspase-8 activation

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