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It was first visualized by electron microscopy in 1973

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The Columbian veterinarians found that "the allele T of the rs22372411 variant was over-represented in MMVD patients compared with healthy controls." They concluded: "Our results show for the first time an association of the rs22372411 COL1A2 gene variant with susceptibility to canine myxomatous mitral valve disease." In a June 2017 abstract, Cornell University veterinary researchers conducted a genome-wide association study (GWAS) which revealed a strong association signal on Chromosome 17, near the CTNNA2 gene, which codes for alpha-catenin

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It was pleasantly received by both Lipa [105] and BBC Radio 1 DJ Greg James, the latter quipping on Twitter "Ben's made you [the BBC] a new theme tune and it's a certified banger