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Within the lung tumor microenvironment, CPT1Aa master regulator of fatty acid -oxidationcooperates with macrophage-derived L-carnitine to orchestrate a dual outcome: conferring resistance to ferroptosis while simultaneously impairing the antitumor function of CD8 + T lymphocytes ( Structurally characterized by up to four BCL-2 homology (BH) domains that govern protein interactions, the BCL-2 protein family is divided into three functionally opposing categories: multi-domain pro-survival members (e.g., BCL-2, BCL-XL, MCL-1), which inhibit apoptosis by sequestering BH3-only initiators (such as BIM, PUMA) and multi-domain effectors (BAX/BAK)

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Systematic review: Quantitative Susceptibility Mapping (QSM) of brain iron profile in neurodegenerative diseases

Gong, J., Mou, T., Wu, H

The significant increases in serum triiodothyronine (T3), thyroxine (T4), and T3/T4 ratio in NPs-treated groups compared to the control and saline groups confirmed the crucial role of the prepared NPs in enhancing thyroid activity and metabolic regulation