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The existing body of literature underscores the challenges associated with GSH's poor bioavailability, attributed to its unfavorable biochemical and pharmacokinetic properties 10,16

If there is insufficient active B2 (as FAD) or NADPH levels, glutathione is not likely to be recycled sufficiently and may lead to GSSG radical formation

Reduced astrocytic presence impaired glutamate clearance and K + buffering thus affecting synaptic plasticity

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Supplementary Information 12951_2024_2575_MOESM1_ESM.docx (download DOCX Additional file 1

TB500 promotes cell migration, cytoskeletal reorganization, and new blood vessel formation in preclinical modelskey steps in early wound healing and longterm tissue remodeling