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The distinction between a systemic and a localized route matters more than it might appear

Frequency ranges from nightly to several times per week depending on clinical goals and patient response

While the anti-aging implications have not been studied directly in humans, the mechanistic pathway is well-established and suggests potential benefits for anti-aging applications

A 2025 systematic review in the American Journal of Sports Medicine confirmed preclinical support across tendon, ligament, muscle, and bone repair models while explicitly noting the absence of human clinical trial data (DOI: 10.1177/15563316251355551)

The patients vital signs and overall condition are monitored to detect any adverse reactions to the therapy, such as allergic reactions, infections, or fluid overload