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This effect may be associated with a decrease in the expression of caspase-1 and IL-18 in cardiac tissue caused by AS-IV through the targeted inhibition of NLRP3 inflammasome activation (41)

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The neurotransmitter imbalance theory still holds partial truth

, a free radical scavenger (17, 29)) against the early paracetamol lesions development, and even more importantly, when the original damaging process induced by an extreme paracetamol over-dose was highly advanced