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Emodin inhibits proliferation and drug efflux, enhances Cisplatin (DDP)-induced apoptosis and DNA damage, and decreases P-gp protein expression in a dose-dependent manner in NSCLC (A549 and H460) cells

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10.1089/ars.2005.7.308 144 VirtamoJ.RapolaJ

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The perception of electrophilic / oxidative stress in acinar cells as the obligate intermediate phenotype in the pathogenesis of chronic pancreatitis (Figure 1) fulfils a set of postulates derived from Kochs classical work on tuberculosis, as modified for a polygenic disease (23,24)