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Another, multicenter, randomized, placebo-controlled study from South Korea assessed changes from baseline on the Alzheimers Disease Assessment Scale-cognitive subscale (ADAS-cog) to investigate the safety and effectiveness of choline alphoscerate for improving cognitive function in 100 overall healthy patients with MCI (Jeon et al., 2024)

IS provided expert opinion and contributed to the writing of the manuscript

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Results Molecular analysis reveals structural stability of GRLX and pKa of individual cysteines Given the previous observations that GLRX can be inactivated via an oxidative mechanism 8,23 , herein we sought to investigate the relative vulnerability of each of the individual cysteines towards GSSG, a model glutathionylating agent, or H 2 O 2 and their contribution to oxidative inactivation

Occupational and environmental exposures to this toxic metal remain a global health problem [1]

doi: 10.3389/fphar.2023.1229297