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The two genes involved in the study are HIF-1 and Nrf-2

Parisi, M

Metalloproteine: das Protein enthlt ein oder mehrere Metall-Atome oder -Ionen

Hou X, Chen Y, Li X, Gu X, Dong W, Shi J, Ji S (2024) Protein succinylation: regulating metabolism and beyond

Macrophages that were infected with viruses carrying the GR mito -EGFP gene and treated with 0.01 to 0.1 g/mL doxycycline to induce transgene expression showed EGFP expression exclusively in the mitochondria (Figure 1B), whereas adenovirus-mediated expression of GR cyto -EGFP showed a cytosolic expression pattern (Figure 1B)

Quality of weight loss (body composition): evidence suggests a greater reduction in fat mass, without a disproportionate increase in lean mass loss, in body-composition sub-studies