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Reye-like syndrome associated with valproic acid

Diabetes 2002;51:2619-28

Patients with this syndrome may also have microcephaly and motor difficulties

Neuroinflammation, vascular dysfunction, and cellular dysfunction regarding astrocytes and neurons have been discussed as underlying mechanisms contributing to these structural and functional alterations [94]

[152] have used transcriptomics and metabolomics approaches to reveal disrupted lipid and energy metabolism, altered amino acid profiles and shifts in hormone synthesis pathways in zebrafish exposed to parabens

FPLC analysis revealed that plasma LDL-C in the HCD + ALC group exhibited a decreasing trend, whereas HDL-C showed an increasing trend (Figure 2D)