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It is an aldosterone antagonist that has a 67% affinity for the receptor for testosterone

doi: 10.1210/endo-128-5-2239 78 HanSYKaneGCheongIHerbisonAE

The bioavailability of natural products varies widely based on their chemical structure, which influences absorption and metabolism [98, 99]

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The propensity score was constructed from age at the index date (continuous), sex, race, region, number of RMS relapses in the preindex period (0, 1, 2+), prior DMT in the preindex period, RMS disability in the preindex period, Deyo-Charlson comorbidity index (DCCI) in the preindex period (continuous), and Psychiatric Diagnosis Group index in the preindex period (continuous)

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