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Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of atgl, hsl, and ampk

heilmannii s.l

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The fact that autophagy-related factors (e.g., BECN1, mTOR, AMPK) can regulate specific regulatory ferroptosis networks also provides us with a new idea as to whether the occurrence of ferroptosis is somehow related to the signaling pathways that regulate autophagy

In addition, LKB1 inactivation, in conjunction with KRAS G12D mutation, promotes serine biosynthesis, contributing to DNA methylation and the enrichment at retrotransposon elements associated with their transcriptional silencing [102]