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A diagnostic algorithm for pyruvate dehydrogenase complex deficiency has been recommended, and the reader is referred to Figure 2 in the 2017 article by Shin and colleagues (72)

Further, the Ligand Docking and extra precision (XP) module was utilized for the molecular docking 28

Elderly patients may be more sensitive to the medications effects and may require slower titration or lower maintenance doses, particularly if they have reduced renal function or are at higher risk for dehydration from gastrointestinal adverse effects

This allows your body to build a tolerance and adapt more gradually

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