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Blood samples were obtained at the start and end of the 2-week trial, during which patients were randomly assigned to receive either active supplementation (2 softgels/day corresponding to ALA 600 mg/day) or no supplementation at all

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10.1111/j.1582-4934.2008.00344.x [DOI] [PMC free article] [PubMed] [Google Scholar] 74.Lin CW, Wu MJ, Liu IY, Su JD, Yen JH

This suggests that cell wall adsorption alone is insufficient for meaningful AFB1 reduction in this strain and highlights the importance of enzymatic or transporter-mediated mechanisms that require live, metabolically active cells

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This suggests that BMAL1 may regulate the function of HIF-1