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doi: 10.3389/fpls.2025.1425880 Received 30 April 2024 Accepted 09 January 2025 Published 20 February 2025 Volume 16 - 2025 Edited by Maria Raffaella Ercolano, University of Naples Federico II, Italy Reviewed by Eva Nouri, Universit de Fribourg, Switzerland Marija Vidovic, University of Belgrade, Serbia Updates Copyright 2025 do Carmo Santos, Silva Santos, Pereira Silva de Novais, dos Santos Lopes, Pirovani and Micheli

Theoretical concerns about chromatin remodeling include potential activation of silenced oncogenes or transposable elements

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Key scientific figures and citations Cagrilintide is a long-acting amylin analogue that, when combined with semaglutide, produced clinically meaningful and dose-dependent weight loss in adults with overweight or obesity. Enebo LB

Other studies, however, have shown that the phenotype described by Allens rule can be replicated under laboratory conditions, suggesting that it might represent growth plasticity rather than a thermoregulatory adaptation to climate