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Despite these limitations, disopyramide remains useful in hypertrophic cardiomyopathy with LVOTO (left ventricular outflow tract obstruction), where its negative inotropy may reduce obstruction and lower the risk of SCD and ventricular arrhythmias in selected patients (24)

Haanp M, Attal N, Backonja M, et al

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These findings make it clear that it is possible to target fat loss without affecting energy homeostasis in other nutrient pathways, opening the door for a deeper exploration of human energy regulation and methods of manipulating it