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ROS is a common signal that activates the NLRP3 inflammasome [135]

In vivo and in vitro studies have shown that Klotho enhances renal tubular cell autophagy and contributes to kidney protection via activation of AMPK and ERK and contributes to kidney protection pathways

15 IL-17 promotes airway remodeling through goblet cell hyperplasia and smooth muscle proliferation, while stimulating structural cells to release neutrophil-activating factors like CXCL8/IL-8, granulocyte-macrophage colony-stimulating factor (GM-CSF), and TNF-

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At specific time points (0, 4, 8, 24 and 48 hours), 1.0 mL of nanoparticle suspension was centrifuged at 19354 g for 10 minutes (Centurion Scientific Ltd., UK)