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Moreover, cyclosporin has been found to disrupt the pregnane X receptor (PXR) pathway, which regulates drug-metabolizing enzymes and transporters, leading to impaired bile acid metabolism and cholestasis (Shang et al

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This highlights the necessity for efficient, unambiguous, cost effective and rapid methods to assess if a line is up to the job, with respect to differentiation potential

The methylcobalamin peak with a retention time of 2.978 min was observed to decrease with a commensurate increase in a degradant peak at 4 min

Missing applications frequently means the biological processes triggered by one application may not sustain long enough to produce lasting change

Cells were incubated for 2 h at 37 C in a humidified 5% CO incubator to allow Kupffer cell adherence