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Metastasis is a major factor in the failure of cancer therapy, resulting in a mortality rate exceeding 90% among cancer patients (Steeg, 2006)

Mov Disord 23:768770

Pathways for the biosynthesis of secondary metabolites use precursors synthesizes during glycolysis, the tricarboxylic acid cycle and the pentose-phosphate pathway [18]

Observations regarding energy expenditure are mixed

Tumor Resistance to Ferroptosis Driven by Stearoyl-CoA Desaturase-1 (SCD1) in Cancer Cells and Fatty Acid Biding Protein-4 (FABP4) in Tumor Microenvironment Promote Tumor Recurrence