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Toxins, 5 (12), 2488-2503

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369,370 Later, quantitative real-time PCR analysis demonstrated that the administration of exendin-4, a GLP-1RA, resulted in significant upregulation of thyroid calcitonin mRNA levels in wild-type mice

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This consideration is based on the fact that independent regulation of gliT may have enabled acquisition of functionality beyond a role in gliotoxin biosynthesis or auto-protection