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For example, in pernicious anemia (a major cause), antibodies attack the intrinsic factor (IF), a protein required for the absorption of B12, or the gastric parietal cells, which produce IF in the first place

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Suppl 4 Van der Kooy K, van Hout H, Marwijk H, Marten H, Stehouwer C, Beekman A

It plays a role in promoting fat oxidation, improving glucose utilization, and supporting exercise performance in preclinical and early human studies

Its actually critical to a number of vital cellular functions and believe it or not, despite the fact that it is inside so many beverages and foods, there is still a high chance that you arent getting enough