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Multidrug resistance-associated protein-1 (MRP-1)-dependent glutathione disulfide (GSSG) efflux as a critical survival factor for oxidant-enriched tumorigenic endothelial cells

Luo TT, Zhang ST, Wang YJ et al (2017) Glutathione-stabilized Cu nanocluster-based fluorescent probe for sensitive and selective detection of Hg 2+ in water

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In tumors, persistent ROS elevation increases GSH synthesis and shifts the redox balance, creating a biochemical environment that selectively activates disulfide/diselenide linkers and metal-based GSH-depleting nanoplatforms

Another study identified 16 microglia subclusters in mouse brain tissue 3 days post-permanent distal MCAO

It consists of the dermal papilla at its base, surrounded by matrix cells that divide to form the hair shaft, and enclosed by an outer root sheath that provides structural support