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The combination therapy resulted in significant improvement in pain, fatigue, sleep, and depression compared to duloxetine and pregabalin alone

Energy can be felt almost immediately, and patients leave the clinic feeling like a different person

However, COX-1 is expressed at some sites of inflammation

Case presentation This case describes a 40-year-old Iranian woman with a decade-long history of nonspecific symptoms, including fatigue, widespread musculoskeletal pain, paresthesia, cognitive disturbances, and optic neuritis