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Vitamin B12 deficiency can have serious medical consequences including irreversible neurological damage

Shavlakadze T, Winn N, Rosenthal N, Grounds MD (2005) Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle

Despite its importance, many people experience a deficiency due to dietary restrictions or absorption issues

That said, its important not to use B12 indiscriminately

On This Page Indications and Usage Dosage and Administration Dosage Forms and Strengths Contraindications Warnings and Precautions Adverse Reactions/Side Effects Drug Interactions Use In Specific Populations Overdosage Description Clinical Pharmacology Nonclinical Toxicology Clinical Studies How Supplied/Storage and Handling Patient Counseling Information Medication Guide Highlights of Prescribing Information NEXIUM (esomeprazole magnesium) delayed-release capsules, for oral use NEXIUM (esomeprazole magnesium) for delayed-release oral suspension Initial U.S

Most observational studies have found a correlation between low serum vitamin B12 concentrations and poor cognitive function, suggesting that low vitamin B12 status may be a risk factor for cognitive decline