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NSAIDs cause topical mucosal damage by inhibiting COX-1, resulting in a decreased level of prostaglandins, which protect the gastric mucosa, and thereby resulting in damage in both the upper and lower gastrointestinal tracts (GITs) [12]

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Il est galement important d'viter les facteurs de stress oxydatif tels que l'alcool ou la fume de cigarette, qui peuvent dgrader le glutathion dans l'organisme

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