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A systematic analysis of idiosyncratic DILI cases with Roussel Uclaf Causality Assessment Method (RUCAM) showed that most drugs are metabolized by CYP isoforms of which CYP3A4/5 is used close to 50% of the time, followed by CYP2C9, CYP2E1, CYP2C19, CYP1A2, and CYP2D6 [12]

Sig Transduct Target Ther 2:17036

With their good safety profiles in addition to their capacity to keep a check on the pro-inflammatory cytokine levels all the while without compromising on the ability of the immune system to respond to the SARS-CoV-2

Brain Iron metabolism

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