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Traditional antibiotic coatings are increasingly limited by poor biofilm penetration and the growing threat of AMR, prompting the development of material-based approaches that integrate physical, chemical, and biological mechanisms for localized infection control

Mechanistically, after trivalent iron ions (Fe 3+ ) are reduced to divalent iron ions (Fe 2+ ), they undergo self-phase separation to form storage compartments for Fe 2+ via metal reductase STEAP [107, 108]

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Cancer cells exploit these modified expression patterns to support and accelerate their proliferation