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In the BRAF mutant cell lines M229P and M238P, we observed that cell lines begin with different initial differentiation stages as defined by their subtype signatures, but shift notably towards the undifferentiated signature upon acquired resistance to vemurafenib (M229R, M238R) (Figure 2A)

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"Glutathione and mitochondria." Frontiers in Pharmacology, 2014

Several reports report the formulation of multifunctional nano gels that combine drug delivery with imaging capabilities, which helps in enabling real-time monitoring of PD treatment efficacy (139)