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Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction

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215 Conclusions Over the past 20 years, increasing interest in the roles that fibroblasts play in both FD and IMID has revolutionized our understanding of these cells

However, similar to the TS-selective inhibitor RTX, TS inhibition by pemetrexed, as indicated by elevations in plasma dUrd concentrations, was relatively transient