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Investigations cluster into four broad domains: All of the above derives from in-vitro and animal studies and is provided strictly for scientific context

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In the study, scientists investigated the differences between skin bacteria from people prone to acne and bacteria from people with clear-skinned faces

One more realistic animal model is that induced by cecal ligation and puncture (CLP), where puncturing the cecum causes the release of fecal material in the peritoneum that results in a polymicrobial peritoneal sepsis

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