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Morris G, Walder KR, Berk M, Marx W, Walker AJ, Maes M, et al

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Mitochondrial dysfunction and associated changes in intestinal epithelial functions are emerging concepts in the pathogenesis of IBD, suggesting impaired metabolic flexibility of epithelial cells affects the regenerative capacity of the intestinal tissue

Also, given that ferroptosis is not a common feature of all patients, treatment with ferroptosis inhibitors in MASLD patients without hepatic ferroptosis might lead to negative trial results

(2005) reported that TQ (1 mg/kg per day for 10 days) was effective in blocking perivascular cuffing and mononuclear cell infiltration in the brain and spinal cord, enhancing red blood cell glutathione (GSH), and inhibiting NF-B activation in the brain and spinal cord