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Description

Epitalon (also known as Epithalon or Epithalamin ) is a synthetic tetrapeptide composed of the amino acid sequence Ala-Glu-Asp-Gly, structurally related to peptides originally identified in pineal gland research

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Physiol 1916, 50, 187188

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Das Peptid besteht aus 15 Aminosuren mit der Sequenz Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val und gehrt zur Familie der Body Protection Compounds

The principal mechanisms underlying this modulation include regulation of hydrolytic enzyme activity, generation of ROS during phagocytosis, chemokine-driven recruitment, formation of neutrophil extracellular traps (NETs), and control of inflammatory cytokine secretion