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2) The receptor-dependent pathway refers to the direct binding of the LIR motif mitophagy-related receptor to LC3, independent of ubiquitination, and the transport of damaged or redundant mitochondria to autophagosomes to achieve mitochondrial selective autophagic degradation

Several pathways contribute to ROS production, including the mitochondrial electron transport chain, inflammatory signaling, and endoplasmic reticulum stress (Ralph et al., 2010)

Second, the reason why CoQ can promote the reduction of oxygen to form H 2 O 2 was not clearly explained by our data and needs to be elucidated through future studies

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Ryu J.K., Rafalski V.A., Meyer-Franke A., Adams R.A., Poda S.B., Rios Coronado P.E., Pedersen L.O., Menon V., Baeten K.M., Sikorski S.L., et al

The amino acid sequences of A42 and A40, as well as sequences of other A peptides discussed in this review, are shown in FIGURE 7