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1b) [31, 37,38,39]

10.1093/advances/nmy052 128 MarquesJ

This matters because visceral adiposity drives metabolic disease far more potently than subcutaneous fat

The mechanism of action of these mitochondria is still up for debate, though

Consistent with this mechanism, Tat upregulates miR-505, which represses SIRT3, leading to ROS accumulation, mitochondrial stress, and a senescence-like microglial phenotype