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After suppressing the expression of PTBP1 in astrocytes, these cells can efficiently trans-differentiate in situ into functional neurons within weeks to months, which improves the motor function of PD mouse models

doi: 10.14797/mdcvj.293 [DOI] [PMC free article] [PubMed] [Google Scholar] 289.International Stroke Trial Collaborative Group

Interestingly, SSBP1, a protein that is essential for mtDNA stability and replication during mitochondrial biogenesis, was increased by APOE4 in females and decreased by APOE4 in males, reflecting a sex-divergent response to APOE4 in the regulation of the same mitochondrial protein

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Rare allergic reactions, such as swelling or hives, are possible

Duration: At 0.51ml per week, a 10ml vial provides approximately 10 weeks of supply