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Obese mice and rats treated with AOD9604 showed significant decreases in adipose tissue depot weights, reductions in adipocyte size observed histologically, and improvements in body composition measured by DEXA scanning or MRI

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This dual approach supports energy, repair, inflammation, and metabolism more consistently, potentially delaying age-related decline

This timing aligns with natural fat metabolism cycles and allows the peptide to work throughout the day when metabolic activity is highest

9 By this effect, onabotulinumtoxinA decreases afferent nerve impulses to suppress neurogenic inflammation and prevent peripheral sensitization

AOD-9604 demonstrates selectivity for beta-3 receptors, which are predominantly expressed in adipose tissue