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Critically, the study documented no significant changes in oral glucose tolerance tests, no alterations in fasting insulin levels, and no changes in serum IGF-1 concentrations across all treatment groups

(PubMed) Smith AD, Smith SM, de Jager CA, et al

It represents a precautionary approach given limited long-term data rather than a response to documented concerns

Alternatively, oral supplements can be used alongside occasional injections depending on symptoms and lab results

Medical history: existing conditions and prior treatments shape whether a peptide is appropriate at all

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