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Digestive Issues: Some users report bloating, abdominal cramps, or loose stools during the first few days

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Specifically, we assayed 31 neurotransmission-related metabolites that might have some relevance to MDD pathophysiology, based on published literature, including compounds from the tryptophan, tyrosine, and purine pathways, in plasma samples from 290 MDD patients at baseline, 4-, and 8 weeks of escitalopram/citalopram treatment

Xu Q, Ensign LM, Boylan NJ et al (2015) Impact of surface polyethylene glycol (peg) density on biodegradable nanoparticle transport in mucus ex vivo and distribution in vivo