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10.1007/s00403-013-1332-y [DOI] [PubMed] [Google Scholar] 56.Lin SX, Lisi L, Dello Russo C, Polak PE, Sharp A, Weinberg G, et al

Although initial studies suggested that GSH depletion was only a byproduct of oxidative stress generated during cell death, recent discoveries suggest that GSH depletion and post-translational modifications of proteins through glutathionylation are critical regulators of apoptosis

Since it was discovered more than 40 years ago, much has been uncovered about this important chemical messenger

Reserves range from 1-6 mg in healthy adults (and can be significantly higher at the upper end of the range), with 2-3 mg being the most common average

SL flies were rich in major lipids, including fatty acids (fatty acid methyl esters, FAMEs) and triacylglycerol (TAG), and were starvation resistant, providing evidence of lipid accumulation (Fig

When it has the resources needed, the liver can eliminate many toxins directly through the stool, bile, or urine