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Reduced GPX4 (glutathione peroxidase 4) activity and GSH levels were also observed (219)

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation

Impaired catabolism of branched-chain amino acidsmodulated by pathogenic variants in BCKDHA and loss-of-function alleles in PPM1Kcompromises tissue-selective disposal of these metabolites, thereby fostering insulin resistance and accelerating the progression of type 2 diabetes mellitus (30)

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Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement