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This can take several shots to correct over several weeks in total, as it takes time for your body to both absorb the vitamin B12 and use it to repair any damaged tissues or boost cell DNA synthesis back to normal levels

wherein the cation has at least two non-hydrogen substituents at positions R 2 -R 8

M., Gratzl, S., et al

Similarly, if you use proton pump inhibitors or H2 receptor antagonists for acid reflux or peptic ulcers, your stomach acid levels may decrease, making it harder for your body to absorb B12 from your diet

Biochem Pharmacol 147:141152

The lack of information is because of insufficient human clinical trials