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In total, 90176 cells were analysed per condition

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with exception of MYO1E, a myosin we detected to be more abundant in tumor (Supplementary Data 2) and which was recently proposed as an independent marker of mortality in lung cancer 25

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SAAM cluster B enriched activated CD4 T cells, CD56bright natural killer cells, type 17 T helper cells, and type 2 T helper cells, which play crucial roles in recognizing and attacking cancer cells 41,42