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In clinical practice, dull or uneven skin tone is often related not only to sun exposure, but also to internal factors such as: Oxidative stress Chronic stress and lack of sleep Low-grade inflammation Reduced cellular repair capacity When these factors accumulate, skin recovery slows downeven with good skincare routines

10.1016/j.tifs.2020.01.010 Summary Keywords green tea polyphenols (GTPs), aging, antioxidants, D-galactose, inflammatory cytokines, Nrf2 signaling pathway Citation Wang D, Wang T, Li Z, Guo Y and Granato D (2022) Green Tea Polyphenols Upregulate the Nrf2 Signaling Pathway and Suppress Oxidative Stress and Inflammation Markers in D-Galactose-Induced Liver Aging in Mice

doi: 10.1186/s10194-015-0516-6 83

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Data availability The tumor RNA-seq data generated in this study have been deposited in the SRA database under accession code PRJNA1280553