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Three months after the infusion, the patient achieved complete clinical remission, including the resolution of proteinuria and seroconversion of double-stranded DNA (dsDNA) autoantibodies

Research indicates that E binds to ER within the cell nucleus, activating the expression of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1)

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224 Although a causal link between hearing loss and dementia or Alzheimer disease has yet to be conclusively established, there is relative consensus that age-related hearing loss is closely associated with cognitive impairment, cognitive decline, and dementia