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Description

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Tumour microenvironment and metabolic plasticity in cancer and cancer stem cells: Perspectives on metabolic and immune regulatory signatures in chemoresistant ovarian cancer stem cells

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Exp Neurol 244:410

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We also found that auranofin is an efficient inhibitor of pure TGR ( K i = 10 nM), able to kill parasites rapidly in culture at physiological concentrations (5 M), and able to partially cure infected mice (worm burden reductions of ~60%)

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Glutamine also supports the production of aspartate, using the cytosolic isoform of aspartate aminotransferase, GOT1

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Studies in which these cytokines were blocked or absent showed significantly impaired fracture healing

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