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4.4.4 Targeting synaptic dysfunction Synaptic dysfunction is widely recognized as one of the earliest and strongest correlates of cognitive decline in AD

A randomized, double-blind, placebo controlled, parallel group, efficacy study of alpha BRAIN administered orally

In each case, a dose of 100 l of the medication was applied to the skin on the back of a mouse

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If the research project targets the multipurpose regeneration of injured tissue, the two are not interchangeable: they target different stages of the healing cascade

Activated Wnt/-catenin signalling enhanced net DAergic neurogenesis in parkinsonian rats by regulating pro-neural genes (Nurr-1, Pitx-3, Ngn-2, and NeuroD1) and mitochondrial biogenesis